Intracellular Transport: Force Controls Motor Switching at Filament Junctions
نویسنده
چکیده
How does cellular traffic switch direction on microtubules, or switch back and forth between microtubule- and actin-based tracks? A pair of recent studies mimics the layout of motors and tracks within the cell to provide intriguing answers to these questions.
منابع مشابه
Filament-Filament Switching Can Be Regulated by Separation Between Filaments Together with Cargo Motor Number
How intracellular transport controls the probability that cargos switch at intersections between filaments is not well understood. In one hypothesis some motors on the cargo attach to one filament while others attach to the intersecting filament, and the ensuing tug-of-war determines which filament is chosen. We investigate this hypothesis using 3D computer simulations, and discover that switch...
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عنوان ژورنال:
- Current Biology
دوره 20 شماره
صفحات -
تاریخ انتشار 2010